HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Oxo-4-imidazolinecarboxylic acid → N-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-oxo-4-imidazolidinecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Oxo-4-imidazolinecarboxylic acid | HCID 89477 | — |
| Reactant | 3-(2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline | HCID 49852105 | — |
| Product | N-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-oxo-4-imidazolidinecarboxamide | HCID 57478291 | 51% |
Reaction Steps
The title compound was prepared in 51% yield according to the general procedure for the preparation of the amides (Method C) starting from 3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline (D6) and 2-oxo-4-imidazolidinecarboxylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07459456B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-87d67397493d4050ad865e9d69b62419 |
| Source note | uspto-grants-2008_12 |