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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2373579Generated: October 29, 2026

Methyl chloroformate → Methyl (3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)carbamate

https://huagongshe.com/reaction/2373579

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl chloroformateHCID 6586—
Reactant3-(2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}anilineHCID 49852105—
ProductMethyl (3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)carbamateHCID 4985067241%

Reaction Steps

The title compound was prepared in 41% yield according to the general procedure for the preparation of carbamates (Method D) starting from 3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline (D6) and methyl chloroformate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07459456B2
Source datasetuspto-grants-2008_12
ORD IDord-7844a2dfb4c74d7bb0967f78b2a43505
Source noteuspto-grants-2008_12