Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2373636Generated: October 30, 2026

Acetyl chloride → N-(2-(Methoxy)-3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)acetamide dihydrochloride

https://huagongshe.com/reaction/2373636

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetyl chlorideHCID 6367—
Reactant2-(Methoxy)-3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}anilineHCID 57444345—
ProductN-(2-(Methoxy)-3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)acetamide dihydrochlorideHCID 5747836542%

Reaction Steps

The title compound was prepared in 42% yield according to the general procedure for the preparation of amides (Method B) starting from starting from 2-(methoxy)-3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline and acetyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07459456B2
Source datasetuspto-grants-2008_12
ORD IDord-b5c4c382490e4449b94b8d652d1ac36e
Source noteuspto-grants-2008_12