HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Trimethylacetamide → N-(4-Fluoro-3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2,2-dimethylpropanamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Trimethylacetamide | HCID 12957 | — |
| Edukt | 5-{4-[2-(5-Bromo-2-fluorophenyl)ethyl]-1-piperazinyl}-2-methylquinoline | HCID 57444350 | — |
| Produkt | N-(4-Fluoro-3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2,2-dimethylpropanamide | HCID 57444352 | 52% |
Reaktionsschritte
The title compound was prepared in 52% yield according to the general procedure for the preparation of amides, ureas and carbamates (Method A) starting from 5-{4-[2-(5-bromo-2-fluorophenyl)ethyl]-1-piperazinyl}-2-methylquinoline and 2,2-dimethylpropanamide.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07459456B2 |
| Quelldatensatz | uspto-grants-2008_12 |
| ORD ID | ord-a315a43c57744d1f8c08d08e7a93f2c4 |
| Quellennotiz | uspto-grants-2008_12 |