Menthol → (-)-Menthol

Participants

Reaction Conditions

Reaction Steps

50 ml of acetonitrile was added to 16.3 g of crude menthol (chemical purity of (L)-menthol: 95%; optical purity: 97.3% e.e.), and the mixture was warmed to 30° C. to dissolve. This solution was cooled to 5° C., and crystals precipitated were collected by filtration and distilled to obtain 11.8 g (yield: 72%) of purified (L)-menthol. Chemical purity: >99%; optical purity: 99.6% e.e.

Provenance & Evidence