HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(4-Nitrophenyl)-2-furancarboxylic acid → N-(3,5-di-t-butyl-4-hydroxyphenyl)-5-(4-nitrophenyl)-2-furan carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(4-Nitrophenyl)-2-furancarboxylic acid | HCID 161593 | — |
| Reactant | 4-Amino-2,6-di-tert-butylphenol | HCID 314220 | — |
| Reactant | 2-(4-((Tert-butoxycarbonyl)amino)phenyl)acetic acid | HCID 2824993 | — |
| Product | N-(3,5-di-t-butyl-4-hydroxyphenyl)-5-(4-nitrophenyl)-2-furan carboxamide | HCID 21918768 | 56% |
Reaction Steps
The experimental protocol used is the same as that described for intermediate 40.1, 2,6-di-t-butyl-4-aminophenol and 5-(4-nitrophenyl)-2-furan carboxylic acid replacing thiazolidine and 4-(t-butoxycarbonylamino)-benzeneacetic acid respectively. The expected compound is obtained in the form of a colourless oil with a yield of 56%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07459558B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-54eac4814ede41ea817293f85b5b4fe3 |
| Source note | uspto-grants-2008_12 |