Dimethylformamide → HCID 21921297, compound

Participants

Reaction Steps

To 1.0 g (2.5 mmol) of resin-bound naphthoic acid was added a mixture of 1.5 g (7.5 mmol) of 4-Bromophenethylamine, 7.5 mL (7.5 mmol) of 1.0 M DIC in DMF, 7.5 mL (7.5 mmol) of 1.0 M HOBt in DMF, and a catalytic amount of DMAP. The resulting mixture was left on a shaker overnight. The resin was washed with DMF, MeOH, DCM three times of each to give resin-bound N-2-(4-Bromophenyl)ethyl-3-hydroxyl-2-naphthamide.

Provenance & Evidence