4-(Trifluoromethyl)phenylboronic acid → HCID 11786625, compound

Participants

Reaction Steps

The resin-bound 3-(4-bromo-phenyl)-(2S)-[(4′-trifluoromethyl-4-hydroxy-biphenyl-3-carbonyl)-amino]-propionic acid methyl ester (30 mg, 0.09 mmol) prepared as described in Example 1 was reacted with 4-trifluoromethyl-phenyl boronic acid (86 mg, 0.45 mmol) by following procedure D to give the title compound (24 mg).

Provenance & Evidence