HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-4-fluorophenylboronic Acid (contains varying amounts of Anhydride) → HCID 69208602, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-4-fluorophenylboronic Acid (contains varying amounts of Anhydride) | HCID 2734660 | — |
| Reactant | Boc-3-bromo-D-phenylalanine | HCID 7006629 | — |
| Product | HCID 69208602 | HCID 69208602 | 81.4% |
Reaction Steps
2-(R)-tert-Butoxycarbonylamino-3-(3′-chloro-4′-fluoro-biphenyl-3-yl)-propionic acid (0.93 g ) was prepared from (R)—N-Boc-3-bromophenylalanine (1.0 g, 2.9 mmol) and 3-chloro-4-fluorophenylboronic acid (1.0 g, 5.8 mmol) following general procedure D.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07459472B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-e3c3a33f55f5435aa7b70e865dd20947 |
| Source note | uspto-grants-2008_12 |