反应详情

3-(3′-Chloro-4′-fluoro-biphenyl-4-yl)-2-(R)-[(4-methoxy-4′-trifluoromethyl-biphenyl-3-carbonyl)-amino]-propionic acid methyl ester (223 mg) was prepared from 4-Methoxy-4′-trifluoromethyl-biphenyl-3-carboxylic acid (141 mg, 0.5 mmol) and-2-(R)-amino-3-(3′-chloro-4′-fluoro-biphenyl-4-yl)-propionic acid methyl ester (155 mg, 0.5 mmol) following the general procedure A.