Methanamine, N-methoxy-, hydrochloride (1:1) → HCID 86597138, compound

Participants

Reaction Steps

4-Methoxy-4′-trifluoromethyl-biphenyl-3-carboxylic acid [2-(3′-chloro-4′-fluoro-biphenyl-4-yl)-1-(R)-(methoxy-methyl-carbamoyl)-ethyl]-amide (0.13 g) was prepared from the 3-(3′-Chloro-4′-fluoro-biphenyl-4-yl)-2-(R)-[(4-methoxy-4′-trifluoromethyl-biphenyl-3-carbonyl)-amino]-propionic acid (0.16 g, 0.28 mmol) and N,O-dimethylhydroxylamine hydrochloride (0.027, 0.28 mmol) according to the general procedure A.

Provenance & Evidence