反应详情

4-Ethoxy-3′,5′-bis-trifluoromethyl-biphenyl-3-carboxylic acid [2-(3′-chloro-4′-fluoro-biphenyl-4-yl)-1-(R)-(3-methyl-[1,2,4]oxadiazol-5-yl)-ethyl]-amide (57 mg) was prepared from 2-(3′-chloro-4′-fluoro-biphenyl-4-yl)-1-(R)-(3-methyl-[1,2,4]oxadiazol-5-yl)-ethylamine (33 mg, 0.10 mmol) and 4-Ethoxy-3′,5′-bis-trifluoromethyl-biphenyl-3-carboxylic acid (37 mg, 0.1 mmol) following the general procedure A.