反应详情

Acetic acid 3-[2-(3′-chloro-4′-fluoro-biphenyl-4-yl)-1-(R)-(3-methyl-[1,2,4]oxadiazol-5-yl)-ethylcarbamoyl]-4′-trifluoromethyl-biphenyl-4-yl ester (45 mg) was prepared from 2-(3′-Chloro-4′-fluoro-biphenyl-4-yl)-1-(R)-(3-methyl-[1,2,4]oxadiazol-5-yl)-ethylamine (33 mg, 0.1 mmol) and acetic acid 3-chlorocarbonyl-4′-trifluoromethyl-biphenyl-4-yl ester (34 mg, 0.1 mmol) following the general procedure M.