HCID 68868338, compound → HCID 86597149, compound

Participants

Reaction Steps

4-Methoxy-4′-trifluoromethyl-biphenyl-3-carboxylic acid [2-(3′-chloro-4′-fluoro-biphenyl-3-yl)-1-(R)-(3-methyl-[1,2,4]oxadiazol-5-yl)-ethyl]-amide (0.073 g) was prepared from 2-(3′-Chloro-4′-fluoro-biphenyl-3-yl)-1-(R)-(3-methyl-[1,2,4]oxadiazol-5-yl)-ethylamine hydrochloride salt [0.07 g, 0.19 mmol, prepared from [2-(3′-Chloro-4′-fluoro-biphenyl-3-yl)-1-(R)-(3-methyl-[1,2,4]oxadiazol-5-yl)-ethyl]-carbamic acid tert-butylester following general procedure N] and 4-Methoxy-4′-trifluoromethyl-biphenyl-3-carboxylic acid (0.056 g, 0.19 mmol) following general procedure A.

Provenance & Evidence