HCID 68868338, compound → HCID 86597150, compound

Participants

Reaction Steps

4-Methoxy-4′-trifluoromethyl-biphenyl-3-carboxylic acid [2-(3′-chloro-4′-fluoro-biphenyl-2-yl)-1-(R)-(3-methyl-[1,2,4]oxadiazol-5-yl)-ethyl]-amide (0.081 g) was prepared from 2-(3′-Chloro-4′-fluoro-biphenyl-2-yl)-1-(R)-(3-methyl-[1,2,4]oxadiazol-5-yl)-ethylamine hydrochloride salt (0.075 g, 0.2 mmol) which was prepared from 2-(R)-tert-Butoxycarbonylamino-2-(3′-chloro-4′-fluoro-biphenyl-2-yl)-propionic acid following general procedure N and 4-methoxy-4′-trifluoromethyl-biphenyl-3-carboxylic acid (0.06 g, 0.2 mmol) following general procedure A.

Provenance & Evidence