Boron tribromide → HCID 11330971, compound

Participants

Reaction Steps

4-Hydroxy-3′,5′-bis-trifluoromethyl-biphenyl-3-carboxylic acid [2-biphenyl-4-yl-1-(R)-(3-methyl-[1,2,4]oxadiazol-5-yl)-ethyl]-amide (53 mg) was prepared from 4-benzyloxy-3′,5′-bis-trifluoromethyl-biphenyl-3-carboxylic acid [2-biphenyl-4-yl-1-(R)-(3-methyl-[1,2,4]oxadiazol-5-yl)-ethyl]-amide (70 mg, 0.1 mmol) and boron tribromide (0.25 mL, 0.25 mmol, 1.0 M solution in DCM) following the general procedure P.

Provenance & Evidence