Ethyl bromoacetate → HCID 69207180, compound

Participants

Reaction Steps

To a solution of the 3-Hydroxy-naphthalene-2-carboxylic acid [2-(4-hydroxy-4′-methanesulfonyl-biphenyl-3-yl)-ethyl]-amide (18 mg, 0.039 mmol) was in DMF were added ethylbromoacetate (0.039 mmol) and Cs2CO3 (0.039 mmol, 13 mg). The reaction mixture was for 12 hr and the reaction mixture was diluted with ethylacetate and washed with water. The organic layer was separated, dried and the crude obtained after removal of the solvent was purified on a silicagel column to afford the desired product 5 mg, and 5 mg of bis ester.

Provenance & Evidence