HCID 59852750, compound → HCID 11716669, compound

HRID 2373874Notes

Reaction equation

HRID 2373874 reaction equation
[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([CH:15]([C:19]2[C:24](Cl)=[N:23][CH:22]=[CH:21][N:20]=2)[NH:16][CH:17]=O)[CH:12]=[CH:13][CH:14]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(OC1C=C(C(NC(C2CCC2)=O)C2C(Cl)=NC=C[N:42]=2)C=CC=1)C1C=CC=CC=1>>[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([C:15]2[N:16]=[CH:17][N:20]3[CH:21]=[CH:22][N:23]=[C:24]([NH2:42])[C:19]=23)[CH:12]=[CH:13][CH:14]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 59852750HCID 59852750, compoundHCID 59852816HCID 59852816, compound

Product 1

HCID 11716669HCID 11716669, compound

Procedure

N-[(3-Benzyloxyphenyl)-(3-chloropyrazin-2-yl)-methyl]-formamide: Prepared according to the procedures for Cyclobutanecarboxylic Acid [(3-benzyloxy-phenyl)-(3-chloro-pyrazin-2-yl)-methyl]Amide, White solid, 1H NMR (CDCl3, 400 MHz) δ 5.03 (s, 2H), 6.62 (d, 1H, J=8.0 Hz), 6.88-6.97 (m, 3H), 7.22-7.24 (m, 1H), 7.32-7.41 (m, 5H), 8.29 (bs, 1H), 8.35 (d, 1H, J=2.4 Hz), 8.51 (d, 1H, J=2.0 Hz).

Sources & evidence

ORD record
ord-b20c255652024b3ab79cd95a4fd99545
Source dataset
uspto-grants-2008_12
Patent number
US07459554B2

Reaction notes

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