sodium (1Z)-1-cyanoprop-1-en-2-olate → (2E)-2-[(6-fluoro-1H-indazol-5-yl)methylidene]-3-oxobutanenitrile

Participants

Reaction Steps

The title compound was prepared from 3.7 g (80% purity, 18.0 mmol) 6-fluoro-1H-indazole-5-carbaldehyde (Example 13A) and 2.08 g (19.84 mmol) sodium (1Z)-1-cyanoprop-1-en-2-olate in analogy to the procedure described in Example 9A yielding 2.5 g (61% of th.) of product which was used in subsequent steps without further purification.

Provenance & Evidence