Acetonitrile →

Participants

Reaction Steps

0.63 g (5 mmol) of dimethyl sulfate was added to 1.45 g (5 mmol) of the compound from Step 1.4 in 15 mL of a 1:1 mixture of ethyl acetate and acetonitrile at room temperature. The mixture was allowed to agitate overnight at room temperature and the precipitate was filtered off and washed with a small amount of ethyl ether. This gave 1.8 g (87% of the theoretical) of a pale-yellow salt melting at 141 to 142° C.

Provenance & Evidence