HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → HCID 178420062, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | 1-phenyl-3-(pyridin-2-yl)propane-1,3-dione | HCID 238448 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178420062 | HCID 178420062 | 97.6% |
Reaction Steps
A 250 mL flask was charged with compound (1) (10 g 44 mmol), a magnetic follower and 150 mL of ethanol. Hydrazine monohydrate (2.15 mL, 44 mmol) was added and the mixture refluxed overnight. On cooling the ethanol was removed and the residue recrystallised from methanol to yield 2-(5-phenylpyrazol-3-yl)pyridine (2) as a pale yellow crystalline solid (9.5 g, 97%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07462404B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-0467e63e151840d0873b0b254db1b8ce |
| Source note | uspto-grants-2008_12 |