Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzoyl Peroxide | HCID 7187 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 3-Methoxy-4-methyl-1,5-naphthyridine | HCID 44597503 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | HCID 44596671 | HCID 44596671 | — |
Reaction Steps
To 3-methoxy-4-methyl-1,5-naphthyridine (0.26 g) dissolved in carbontetrachloride (6 ml) was added N-bromosuccinimide (1.2 eq) and benzoyl peroxide (0.3 eq) and heated at 80° C. for 4 h. The reaction was partitioned between satd. NaHCO3 and DCM, and the DCM layer then dried over Na2SO4 to give the title compound (120 mg) after concentration. MS (ESI+) for m/z 252 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07462600B2 |
|---|
| Source dataset | uspto-grants-2008_12 |
|---|
| ORD ID | ord-a1701daab7be460dbe15e9f5d33ba8fa |
|---|
| Source note | uspto-grants-2008_12 |
|---|
