HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2374210Generated: October 31, 2026
Potassium Fluoride → HCID 10156609, compound
https://huagongshe.com/reaction/2374210
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Fluoride | HCID 522689 | — |
| Reactant | 2-Fluorophenylpropyl mesylate | HCID 12071461 | — |
| Reactant | HCID 135797776 | HCID 135797776 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 10156609 | HCID 10156609 | — |
Reaction Steps
A suspension of 1.0 g (4.09 mmol) of 7-hydroxy-2-(pyridin-4-yl)-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one and 0.95 g (4.09 mmol) of 1-[3-(methylsulfonyloxy)propyl]-2-fluorobenzene in 100 ml of anhydrous acetonitrile was treated with 4.1 g (1.42 mmol) of potassium fluoride suspended on alumina (Fluka) and the resulting mixture was heated at 80° C. for 24 h.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07462621B2 |
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| Source dataset | uspto-grants-2008_12 |
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| ORD ID | ord-4a742cac403849d6afbb245937318933 |
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| Source note | uspto-grants-2008_12 |
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