HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 5-Methanesulfonyl-2-thiazol-2-yl-benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 5-Methanesulfonyl-2-thiazol-2-yl-benzoic acid methyl ester | HCID 59853700 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 5-Methanesulfonyl-2-thiazol-2-yl-benzoic acid | HCID 59853738 | 50% |
Reaction Steps
5-Methanesulfonyl-2-thiazol-2-yl-benzoic acid is prepared by saponification of 5-Methanesulfonyl-2-thiazol-2-yl-benzoic acid methyl ester in the presence of sodium hydroxide (2N) in a mixture of dioxane and ethanol at 80 deg for 30 minutes. Brow solid, 50% yield, MS (m/e): 282.2 (M−H, 100%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07462617B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-6c45ec37b3dc410e86b29d080d7e8775 |
| Source note | uspto-grants-2008_12 |