Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrazine | HCID 9321 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 58542168 | HCID 58542168 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 86659976 | HCID 86659976 | 47.9% |
Reaction Steps
4-Chloro-2-propylsulfanyl-pyrimidine (15.03 g), hydrazine (10.69 g) and potassium carbonate (15.37 g) were added to ethanol (150 mL) and the mixture was heated to 80° C. for three hours. The mixture was cooled, filtered, and the filtrate was concentrated under reduced pressure. The residue was chromatographed (CH2Cl2/hexanes through silica) to give 7.036 g of (2-propylsulfanyl-pyrimidin-4-yl)-hydrazine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08642601B2 |
|---|
| Source dataset | uspto-grants-2014_02 |
|---|
| ORD ID | ord-c4419f62a4314e48af9d31adfa747642 |
|---|
| Source note | uspto-grants-2014_02 |
|---|
