HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-Fluoro-4-piperazin-1-ylphenyl)ethanone → 1-{4-[4-(2-Chloro-5-methanesulfonyl-benzoyl)-piperazin-1-yl]-3-fluoro-phenyl}-ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-Fluoro-4-piperazin-1-ylphenyl)ethanone | HCID 685610 | — |
| Reactant | 2-Chloro-5-(methylsulphonyl)benzoic acid | HCID 2329132 | — |
| Product | 1-{4-[4-(2-Chloro-5-methanesulfonyl-benzoyl)-piperazin-1-yl]-3-fluoro-phenyl}-ethanone | HCID 59793716 | — |
Reaction Steps
The title compound was prepared according to the procedure D described for example 2 from 1-(3-Fluoro-4-piperazin-1-yl-phenyl)-ethanone and 2-chloro-5-methanesulfonyl-benzoic acid (Example B), 72%, white solid, M+H+: 439.1)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07462617B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-9399ab17d288474b9070b9b97fe82e44 |
| Source note | uspto-grants-2008_12 |