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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2374263Generated: October 29, 2026

1-(3-Fluoro-4-trifluoromethyl-phenyl)-piperazine → [4-(3-Fluoro-4-trifluoromethyl-phenyl)-piperazin-1-yl]-(5-methanesulfonyl-2-thiazol-2-yl-phenyl)-methanone

https://huagongshe.com/reaction/2374263

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-Fluoro-4-trifluoromethyl-phenyl)-piperazineHCID 59793595—
Reactant5-Methanesulfonyl-2-thiazol-2-yl-benzoic acidHCID 59853738—
Product[4-(3-Fluoro-4-trifluoromethyl-phenyl)-piperazin-1-yl]-(5-methanesulfonyl-2-thiazol-2-yl-phenyl)-methanoneHCID 59853749—

Reaction Steps

The title compound was prepared according to the procedure E described for Example 9 from 1-(3-Fluoro-4-trifluoromethyl-phenyl)-piperazine (Example P) and 5-Methanesulfonyl-2-thiazol-2-yl-benzoic acid (Example O). MS (ISP): 514.5 MH+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07462617B2
Source datasetuspto-grants-2008_12
ORD IDord-9f39c51a17d74ea8bad392506862a3bc
Source noteuspto-grants-2008_12