Dimethyl-(4-piperazin-1-YL-phenyl)-amine → [4-(4-Dimethylamino-phenyl)-piperazin-1-yl]-(4-methanesulfonyl-biphenyl-2-yl)-methanone

HRID 2374272Notes

Reaction equation

HRID 2374272 reaction equation
[CH3:1][N:2]([CH3:15])[C:3]1[CH:8]=[CH:7][C:6]([N:9]2[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]2)=[CH:5][CH:4]=1.[CH3:16][S:17]([C:20]1[CH:21]=[C:22]([C:32](O)=[O:33])[C:23]([C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)=[CH:24][CH:25]=1)(=[O:19])=[O:18]>>[CH3:1][N:2]([CH3:15])[C:3]1[CH:4]=[CH:5][C:6]([N:9]2[CH2:14][CH2:13][N:12]([C:32]([C:22]3[CH:21]=[C:20]([S:17]([CH3:16])(=[O:19])=[O:18])[CH:25]=[CH:24][C:23]=3[C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=3)=[O:33])[CH2:11][CH2:10]2)=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 4738754Dimethyl-(4-piperazin-1-YL-phenyl)-amineHCID 574452544-(methylsulfonyl)-Biphenyl-2-carboxylic acid

Product 1

HCID 59853729[4-(4-Dimethylamino-phenyl)-piperazin-1-yl]-(4-methanesulfonyl-biphenyl-2-yl)-methanone

Procedure

The tide compound was prepared according to the procedure E described for Example 9 from Dimethyl-(4-piperazin-1-yl-phenyl)-amine [91703-23-0] and 4-Methanesulfonyl-biphenyl-2-carboxylic acid (Example V). MS (ISP): 464.3 MH+.

Workup

  1. customThe tide compound was prepared

Sources & evidence

ORD record
ord-b871b386867045bcb3567741d626317d
Source dataset
uspto-grants-2008_12
Patent number
US07462617B2

Reaction notes

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