4-(methylsulfonyl)-Biphenyl-2-carboxylic acid → (4-Methanesulfonyl-biphenyl-2-yl)-[4-(4-methoxy-[1,3,5]triazin-2-yl)-piperazin-1-yl]-methanone

HRID 2374274Notes

Reaction equation

HRID 2374274 reaction equation
[CH3:1][O:2][C:3]1[N:8]=[C:7]([N:9]2[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]2)[N:6]=[CH:5][N:4]=1.[CH3:15][S:16]([C:19]1[CH:20]=[C:21]([C:31](O)=[O:32])[C:22]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)=[CH:23][CH:24]=1)(=[O:18])=[O:17]>>[CH3:15][S:16]([C:19]1[CH:24]=[CH:23][C:22]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)=[C:21]([C:31]([N:12]2[CH2:13][CH2:14][N:9]([C:7]3[N:8]=[C:3]([O:2][CH3:1])[N:4]=[CH:5][N:6]=3)[CH2:10][CH2:11]2)=[O:32])[CH:20]=1)(=[O:17])=[O:18]

Participants

3

Reactant 2

HCID 574452544-(methylsulfonyl)-Biphenyl-2-carboxylic acidHCID 690376682-Methoxy-4-piperazin-1-yl-[1,3,5]triazine

Product 1

HCID 59853690(4-Methanesulfonyl-biphenyl-2-yl)-[4-(4-methoxy-[1,3,5]triazin-2-yl)-piperazin-1-yl]-methanone

Procedure

The tide compound was prepared according to the procedure E described for Example 9 from 2-Methoxy-4-piperazin-1-yl-[1,3,5]triazine [59215-45-1] and 4-Methanesulfonyl-biphenyl-2-carboxylic acid (Example V). MS (ISP): 454.5 MH+.

Workup

  1. customThe tide compound was prepared

Sources & evidence

ORD record
ord-665318921efa42a28ceb5cd695c35d27
Source dataset
uspto-grants-2008_12
Patent number
US07462617B2

Reaction notes

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