HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropanol → 7-Fluoro-5-isopropoxy-3,4-dihydroquinazolin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | 5,7-Difluoro-3,4-dihydroquinazolin-4-one | HCID 135510687 | — |
| Product | 7-Fluoro-5-isopropoxy-3,4-dihydroquinazolin-4-one | HCID 136231400 | 73% |
Reaction Steps
5,7-Difluoro-3,4-dihydroquinazolin-4-one was reacted with isopropanol to give 7-fluoro-5-isopropoxy-3,4-dihydroquinazolin-4-one in 73% yield; NMR Spectrum: (DMSOd6) 1.31 (s, 6H), 4.73 (m, 1H), 6.89 (m, 1H), 6.95 (m, 1H), 7.96 (s, 1H); Mass Spectrum: M+H+ 223.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07462623B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-f777f8ded35d4767b570927d1bae6996 |
| Source note | uspto-grants-2008_12 |