Acetyl chloride → HCID 136335785, compound

HRID 2374490Notes

Reaction equation

[NH2:1][C:2]1[C:3]([C:8]2[NH:22][C:11]3=[CH:12][C:13]4[C:14]([CH3:21])([CH3:20])[C:15](=[O:19])[NH:16][C:17]=4[CH:18]=[C:10]3[N:9]=2)=[N:4][NH:5][C:6]=1[CH3:7].[C:23](Cl)(=[O:25])[CH3:24]>>[CH3:21][C:14]1([CH3:20])[C:13]2[CH:12]=[C:11]3[NH:22][C:8]([C:3]4[C:2]([NH:1][C:23](=[O:25])[CH3:24])=[C:6]([CH3:7])[NH:5][N:4]=4)=[N:9][C:10]3=[CH:18][C:17]=2[NH:16][C:15]1=[O:19]

Participants

Reactant 2

HCID 6367Acetyl chloride

HCID 135501811HCID 135501811, compound

Product 1

HCID 136335785HCID 136335785, compound

Procedure

N-[3-(7,7-Dimethyl-6-oxo-1,5,6,7-tetrahydro-imidazo[4,5-f]indol-2-yl)-5-methyl-1H-pyrazol-4-yl]-acetamide was prepared using 2-(4-amino-5-methyl-1H-pyrazol-3-yl)-7,7-dimethyl-5,7-dihydro-1H-imidazo[4,5-f]indol-6-one (60 mg, 0.21 mmol) and acetyl chloride. The title compound was obtained as white powder (3.7 mg).

Workup

customN-[3-(7,7-Dimethyl-6-oxo-1,5,6,7-tetrahydro-imidazo[4,5-f]indol-2-yl)-5-methyl-1H-pyrazol-4-yl]-acetamide was prepared

Sources & evidence

ORD record: ord-5eea3546fe5c478fbe2a3bce12aa4b15
Source dataset: uspto-grants-2008_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07462639B2

Reaction notes

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