3-(Trifluoromethyl)benzoyl chloride → HCID 178462883, compound

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Reaction Steps

N-[3-(5-Ethyl-7,7-dimethyl-6-oxo-1,5,6,7-tetrahydro-imidazo[4,5-f]indol-2-yl)-1H-pyrazol-4-yl]-3-trifluoromethyl-benzamide was prepared using 2-(4-amino-1H-pyrazol-3-yl)-5-ethyl-7,7-dimethyl-5,7-dihydro-1H-imidazo[4,5-f]indol-6-one (250 mg, 0.81 mmol) and 3-(trifluoromethyl)benzoyl chloride (131 μl, 0.89 mmol). The title compound was obtained as light brown powder (195 mg, 50%).

Provenance & Evidence