6-Bromohexanoyl chloride → 9-(6-Bromohexanoyl)-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-5-one

HRID 2374570Notes

Reaction equation

HRID 2374570 reaction equation
[CH2:1]1[C:10]2[C:5]3=[C:6]([CH2:11][CH2:12][C:13](=[O:14])[N:4]3[CH2:3][CH2:2]1)[CH:7]=[CH:8][CH:9]=2.[Br:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][C:21](Cl)=[O:22]>>[Br:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][C:21]([C:8]1[CH:9]=[C:10]2[C:5]3=[C:6]([CH2:11][CH2:12][C:13](=[O:14])[N:4]3[CH2:3][CH2:2][CH2:1]2)[CH:7]=1)=[O:22]

Participants

3

Reactant 2

HCID 898486-Bromohexanoyl chlorideHCID 136945641,2,6,7-tetrahydro-5H-pyrido[3,2,1-ij]quinolin-3-one

Product 1

HCID 218874359-(6-Bromohexanoyl)-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-5-one

Procedure

Using 2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-5-one and 6-bromohexanoyl chloride according to the same method as that of Reference Example 1, the title compound (3.90 g) was obtained as colorless crystals having a melting point of 52-53° C.

Sources & evidence

ORD record
ord-b486482873704993bb1110af1cdecc2e
Source dataset
uspto-grants-2008_12
Patent number
US07462628B2

Reaction notes

Loading…