1-(2,3-Dihydro-1H-indol-1-yl)ethan-1-one → HCID 21887099, compound

HRID 2374576Notes

Reaction equation

HRID 2374576 reaction equation
[C:1]([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH2:6][CH2:5]1)(=[O:3])[CH3:2].[Br:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19](Cl)=[O:20]>>[C:1]([N:4]1[C:12]2[C:7](=[CH:8][C:9]([C:19](=[O:20])[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][Br:13])=[CH:10][CH:11]=2)[CH2:6][CH2:5]1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 276731-(2,3-Dihydro-1H-indol-1-yl)ethan-1-oneHCID 898486-Bromohexanoyl chloride

Product 1

HCID 21887099HCID 21887099, compound

Procedure

Using 1-acetylindoline and 6-bromohexanoyl chloride according to the same method as that of Reference Example 1, the title compound (1.27 g) was obtained as colorless crystals having a melting point of 110 to 111° C.

Sources & evidence

ORD record
ord-3a3f2fa8621b44b88e3f34f57e4668a5
Source dataset
uspto-grants-2008_12
Patent number
US07462628B2

Reaction notes

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