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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 2374628Erstellt: 25. Oktober 2026

1-Chloro-1,2,3,4-tetrahydronaphthalene → (+/-)-8-{3-[1-(1,2,3,4-Tetrahydro-1-naphthalenyl)-4-piperidinyl]propanoyl}-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one hydrochloride

https://huagongshe.com/reaction/2374628

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt1-Chloro-1,2,3,4-tetrahydronaphthaleneHCID 188717—
Edukt8-[3-(4-piperidinyl)propanoyl]1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-oneHCID 9966544—
Produkt(+/-)-8-{3-[1-(1,2,3,4-Tetrahydro-1-naphthalenyl)-4-piperidinyl]propanoyl}-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one hydrochlorideHCID 218877155,6%

Reaktionsschritte

Using 8-[3-(4-piperidinyl)propanoyl]-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one (500 mg) and (±)-1-chloro-1,2,3,4-tetrahydronaphthalene (280 mg) according to the same method as that of Example 330, the title compound (43 mg) was obtained as pale yellow amorphous powders.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07462628B2
Quelldatensatzuspto-grants-2008_12
ORD IDord-e93668312d2d46a58a331dd0eaa9af32
Quellennotizuspto-grants-2008_12