HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole → 5-(4-Bromo-3,5-dimethylphenyl)-1-methyl-1H-pyrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole | HCID 4912908 | — |
| Reactant | 2-Bromo-5-iodo-1,3-dimethylbenzene | HCID 20748037 | — |
| Product | 5-(4-Bromo-3,5-dimethylphenyl)-1-methyl-1H-pyrazole | HCID 86697138 | — |
Reaction Steps
The title compound is prepared from 2-bromo-5-iodo-1,3-dimethylbenzene and 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole following a procedure analogous to that described in Step 1 of Intermediate 17. LC (method 9): tR=1.11 min; Mass spectrum (ESI+): m/z=265 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08642585B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-c9382651a30f4963b846a6ce59ef1f31 |
| Source note | uspto-grants-2014_02 |