2-Thiophenecarbonyl chloride → HCID 58712002, compound

Participants

Reaction Steps

In a similar manner as described for Intermediate 59, using 6-(1-aminoethyl)-N-[4-(methyloxy)phenyl]-1,2,4-triazin-3-amine (Intermediate 47) (100 mg, 0.41 mmol), and thiophene-2-carbonyl chloride (0.048 mL, 0.45 mmol) to afford N-[1-(3-{[4-(methyloxy)phenyl]amino}-1,2,4-triazin-6-yl)ethyl]-2-thiophenecarboxamide (115 mg) as a yellow solid. MS m/z 356 (M+1).

Provenance & Evidence