Triethylamine → HCID 11453132, compound

Participants

Role	Name	HCID	Charge
Reactant	Triethylamine	HCID 8471	—
Reactant	HCID 45075259	HCID 45075259	—
Reactant	5-Methyl-2-(methylthio)-7-phenylimidazo[5,1-F][1,2,4]triazine	HCID 53471832	—
Reactant	5-Methyl-2-(methylsulfonyl)-7-phenylimidazo[5,1-F][1,2,4]triazine	HCID 53471833	—
Solvent	Ethanol	HCID 702	—
Product	HCID 11453132	HCID 11453132	8.2%

Reaction Steps

Applying the displacement procedure, using 5-methyl-2-(methylthio)-7-phenylimidazo[5,1-f][1,2,4]triazine (Intermediate 72) (50 mg, 0.17 mmol), (4-{[2-(1-piperidinyl)ethyl]oxy}phenyl)amine hydrochloride (45 mg, 0.17 mmol), triethylamine (0.024 mL, 0.17 mmol) and ethanol (2.5 mL) to afford 5-methyl-7-phenyl-N-(4-{[2-(1-piperidinyl)ethyl]oxy}phenyl)imidazo[5,1-f][1,2,4]triazin-2-amine (6 mg) as a yellow solid. MS m/z 429 (M+1).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07462614B2
Source dataset	uspto-grants-2008_12
ORD ID	ord-66d8e0e1c86c4b18b325aae99f5ec414
Source note	uspto-grants-2008_12