HCID 86697169, compound → HCID 86697168, compound

HRID 237507Notes

Reaction equation

HRID 237507 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([S:12]([CH2:15][CH2:16][CH2:17][OH:18])(=[O:14])=[O:13])[CH:5]=[C:6]([CH3:11])[C:7]=1[N+:8]([O-])=O>C(O)C.[Pd]>[NH2:8][C:7]1[C:6]([CH3:11])=[CH:5][C:4]([S:12]([CH2:15][CH2:16][CH2:17][OH:18])(=[O:14])=[O:13])=[CH:3][C:2]=1[CH3:1]

Participants

4

Reactant 1

HCID 86697169HCID 86697169, compound

Product 1

HCID 86697168HCID 86697168, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

3-(3,5-Dimethyl-4-nitro-benzenesulfonyl)-propan-1-ol is dissolved in 15 mL of ethanol, Pd/C(5%) (55 mg) is added and the reaction mixture is stirred under hydrogen atmosphere (3 bar) for 3 h. The reaction mixture is filtered on a celite pad, the solvent is concentrated under vacuum to give the title compound. Yield: 1 g.

Workup

  1. filtrationThe reaction mixture is filtered on a celite pad
  2. concentrationthe solvent is concentrated under vacuum

Sources & evidence

ORD record
ord-54588215d5b14762bb92bef4b58089c6
Source dataset
uspto-grants-2014_02
Patent number
US08642585B2

Reaction notes

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