Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-(4-Methoxybenzyl)phenol → 2-(4-methoxybenzyl)phenyl 2,3,4,6-tetra-O-acetyl-beta-D-glucopyranoside
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-(4-Methoxybenzyl)phenol | HCID 258451 | — |
| 반응물 | alpha-D-Glucopyranose, 2,3,4,6-tetraacetate 1-(2,2,2-trichloroethanimidate) | HCID 10896298 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 2-(4-methoxybenzyl)phenyl 2,3,4,6-tetra-O-acetyl-beta-D-glucopyranoside | HCID 12019984 | 94.1% |
반응 단계
To a solution of 2-(4-methoxybenzyl)phenol (46 mg) and 2,3,4,6-tetra-O-acetyl-1-O-trichloroacetoimidoyl-α-D-glucopyranose (0.13 g) in dichloromethane (2 mL) was added boron trifluoride diethyl ether complex (0.033 mL), and the mixture was stirred at room temperature for 1 hour. The reaction mixture was purified by column chromatography on aminopropyl silica gel (eluent: dichloromethane) to give 2-(4-methoxybenzyl)phenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside (0.11 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07465712B2 |
| 출처 데이터셋 | uspto-grants-2008_12 |
| ORD ID | ord-1f9951b7d6784793bc3c701cd1cd25b3 |
| 출처 메모 | uspto-grants-2008_12 |