HCID 11192384, compound → HCID 11489799, compound

HRID 2375171Notes

Reaction equation

C1C2NC3C(=CC=CC=3)SC=2C=CC=1C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]1CCOC1O)=O)CC(C)C)=O)CC(C)C)=O)CC(C)C)=O.[CH3:48][C:49]([O:73][C:74]1[CH:87]=[CH:86][C:85]2[S:84][C:83]3[C:78](=[CH:79][CH:80]=[CH:81][CH:82]=3)[NH:77][C:76]=2[CH:75]=1)([CH3:72])[C:50]([NH:52][CH2:53][C:54]([NH:56][C@H:57]([C:62]([NH:64][C@H:65]1[CH2:69][CH2:68][O:67][CH:66]1[O:70]C)=[O:63])[CH2:58][CH:59]([CH3:61])[CH3:60])=[O:55])=[O:51]>>[CH3:72][C:49]([O:73][C:74]1[CH:87]=[CH:86][C:85]2[S:84][C:83]3[C:78](=[CH:79][CH:80]=[CH:81][CH:82]=3)[NH:77][C:76]=2[CH:75]=1)([CH3:48])[C:50]([NH:52][CH2:53][C:54]([NH:56][C@H:57]([C:62]([NH:64][C@H:65]1[CH2:69][CH2:68][O:67][CH:66]1[OH:70])=[O:63])[CH2:58][CH:59]([CH3:61])[CH3:60])=[O:55])=[O:51]

Participants

Reactant 2

HCID 11192384HCID 11192384, compound

HCID 11216021HCID 11216021, compound

Product 1

HCID 11489799HCID 11489799, compound

Procedure

The experimental protocol is the same as that described for the compound of Example 2, starting with the compound of Example 59 instead of the compound of Example 1. A beige solid is obtained. Melting point: 127-128° C.

Workup

customA beige solid is obtained

Sources & evidence

ORD record: ord-5114c2bc2d8144b785a9a98963c0c015
Source dataset: uspto-grants-2008_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07465721B2

Reaction notes

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