HCID 69152202, compound → Phenyl(1,2,3,4-tetrahydro-7-isoquinolinyl)methanone

Participants

Reaction Steps

(2-Acetyl-1,2,3,4-tetrahydroisoquinolin-7-yl)-(phenyl)methanone (11.10 mmol, 3.10 g) was heated in hydrochloric acid (7 M, 250 ml) to reflux for 6 h. The resulting mixture was concentrated, made alkaline with sodium hydroxide solution and extracted with ethyl acetate. Drying of the organic phase and concentration resulted in 1.7 g of the title compound as a brown oil.

Provenance & Evidence