HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxyxylidine → 1-[4-acetyl-1-(4-hydroxy-2,3-dimethyl-phenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxyxylidine | HCID 76542 | — |
| Reactant | 3,4-Diacetyl-2,5-hexanedione | HCID 78730 | — |
| Product | 1-[4-acetyl-1-(4-hydroxy-2,3-dimethyl-phenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-ethanone | HCID 69275288 | — |
Reaction Steps
Utilizing the general procedure outlined in Example 48, 1,1,2,2-tetraacetylethane (300 mg, 1.5 mol) and 4-amino-2.3-xylenol (206 mg, 1.5 mmol) reacted to give 1-[4-acetyl-1-(4-hydroxy-2,3-dimethyl-phenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-ethanone as yellow solid: MS (ESI) 300 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07465730B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-8cf72aeb103043469de7829dfe57a48e |
| Source note | uspto-grants-2008_12 |