참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Aluminium lithium hydride | HCID 21226445 | — |
| 반응물 | 2(1H-indol-3-yl)ethylacetyltryptamineacetamide | HCID 86587735 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | N-Ethyltryptamine | HCID 6092 | 185.2% |
반응 단계
Lithium aluminum hydride in tetrahydrofuran (1M, 30 mL) was added dropwise to a stirring solution of N-[2-(1H-indol-3-yl)ethylacetyltryptamineacetamide (2.02 g) in tetrahydrofuran (10 mL) at 0° C. The solution was then heated at reflux overnight. The solution was cooled to 0° C. and water was very carefully added dropwise. The white solid was filtered and rinsed with ether/methanol (9:1, 2×25 mL). The solvent was removed from the filtrate, giving N-ethyl-2-(1H-indol-3-yl)ethanamine as a viscous-pale yellow oil (1.75 g, 93%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07465750B2 |
|---|
| 출처 데이터셋 | uspto-grants-2008_12 |
|---|
| ORD ID | ord-37368a20d5064cdba032289dbebd62d5 |
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| 출처 메모 | uspto-grants-2008_12 |
|---|
