HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-5-iodo-1,3-dimethylbenzene → 4-(4-Bromo-3,5-dimethylphenyl)-1-methylpyridin-2(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-5-iodo-1,3-dimethylbenzene | HCID 20748037 | — |
| Reactant | 1-Methyl-2-oxo-1,2-dihydropyridine-4-boronic acid | HCID 67814299 | — |
| Product | 4-(4-Bromo-3,5-dimethylphenyl)-1-methylpyridin-2(1H)-one | HCID 86697239 | — |
Reaction Steps
The title compound is prepared from 2-bromo-5-iodo-1,3-dimethylbenzene and 1-methyl-2-oxo-1,2-dihydropyridin-4-ylboronic acid following a procedure analogous to that described in Step 1 of Intermediate 56. LC (method 11): tR=1.04 min; Mass spectrum (ESI+): m/z=292, 294 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08642585B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-2211b2ef377a493590653dd29b430aa5 |
| Source note | uspto-grants-2014_02 |