3-(Dimethylamino)-1-propanol → HCID 69215210, compound

HRID 2375765Notes

Reaction equation

HRID 2375765 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][NH:9][C:10](=[O:12])[OH:11].[CH3:13][N:14]([CH3:19])[CH2:15][CH2:16][CH2:17]O>>[C:3]1([CH2:8][O:12][C:10](=[O:11])[NH:9][CH2:8][C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[O:1][CH2:17][CH2:16][CH2:15][N:14]([CH3:19])[CH3:13])[CH:4]=[CH:5][CH:6]=[CH:7][CH:2]=1

Participants

3

Reactant 2

HCID 766463-(Dimethylamino)-1-propanolHCID 21665615HCID 21665615, compound

Product 1

HCID 69215210HCID 69215210, compound

Procedure

By following a procedure analogous to Preparation XCVI starting from the benzyl ester of [(2-hydroxyphenyl)methyl]carbamic acid and 3-(dimethylamino)propanol, the expected product is obtained in the form of a colorless oil (yield=81%).

Workup

  1. customanalogous to Preparation XCVI

Sources & evidence

ORD record
ord-6809fd1d020d4aec9ac642774fd4f251
Source dataset
uspto-grants-2008_12
Patent number
US07465811B2

Reaction notes

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