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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2375773Generated: November 1, 2026

2-Bromo-5-chloro-1-(methoxymethoxymethyl)benzene → 5-Chloro-1-(3-Fluorophenyl)-1,3-dihydrobenzo[c][1,2]oxaborole

https://huagongshe.com/reaction/2375773

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-5-chloro-1-(methoxymethoxymethyl)benzeneHCID 59024677—
Reactant2-(3-Fluorophenyl)-1,3,2-dioxaborolaneHCID 66704745—
Product5-Chloro-1-(3-Fluorophenyl)-1,3-dihydrobenzo[c][1,2]oxaboroleHCID 11207355—

Reaction Steps

This was prepared as per the procedure in Example 11, from 2-(3-fluorophenyl)-[1,3,2]-dioxaborolane and 1-bromo4-chloro-2-((methoxymethoxy)methyl)-benzene to afford white crystalline product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07465836B2
Source datasetuspto-grants-2008_12
ORD IDord-0adb6ef511b342c593862bedac959328
Source noteuspto-grants-2008_12