Potassium Carbonate → HCID 59854582, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of (1H-indazol-5-yl)-(6-iodo-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine (0.076 g), 1-(2-methoxy-ethyl)-2-oxo-1,2-dihydro-pyridine-4-boronic acid (36 mg), PdCl2(PPh3)2 (7 mg) end potassium carbonate (76 mg) in dioxane/wawr (4:1) (5 mL) was heated to 100° C. for 48 h. Purification via chromatograpby afforded tJm title compound as a pale yellow solid. δH 3.30 (3H, s), 3.62 (2H, t), 4.18 (2H, t), 5.99 (1H, dd), 6.89 (1H, d), (7.27 (1H, s), 7.57 (2H, d), 7.69 (2H, m), 8.09 (1H, s), 8.16 (1H, s), 8.18 (1H, s) and 9.67 (1H, s). MH+ 402.13.

Provenance & Evidence