Dabco → HCID 69274229, compound

Participants

Reaction Steps

To a stirred solution of 1M tert-butyl 4-(4-chloro-7H-pyrrolo[2,3-d]-pyrimidin-6-yl)-3,6-dihydropyridine-1(2H)-carboxylate (200 mg, 0.6 mmol) in anhydrous DMSO (0.6 mL), was added 1,4-Diaza-bicyclo[2.2.2]octane (370 mg, 3.3 mmol). The mixture was stirred under argon at rt until TLC analysis showed no starting material was present. The resulting solution containing the title compound was used directly in the next step.

Provenance & Evidence