HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 237591Generated: October 25, 2026
4-Bromopyridazine hydrobromide → 2,6-Dimethyl-4-(pyridazin-4-yl)aniline
https://huagongshe.com/reaction/237591
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Bromopyridazine hydrobromide | HCID 53407906 | — |
| Reactant | 2,6-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline | HCID 56737724 | — |
| Product | 2,6-Dimethyl-4-(pyridazin-4-yl)aniline | HCID 86697255 | — |
Reaction Steps
The title compound is prepared from 4-bromopyridazine hydrobromide and 2,6-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline following a procedure analogous to that described in Step 2 of Intermediate 62. The mixture is stirred for 12 hours at 70° C. LC (method 9): tR=0.66 min; Mass spectrum (ESI+): m/z=200 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08642585B2 |
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| Source dataset | uspto-grants-2014_02 |
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| ORD ID | ord-7d7e54162d134245a1342a2d2b21f54c |
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| Source note | uspto-grants-2014_02 |
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